THERAPEUTIC STRATEGIES IN AN OUTBREAK SCENARIO TO TREAT THE NOVEL CORONAVIRUS ORIGINATING IN WUHAN, CHINA [VERSION 2; PEER REVIEW: 2 APPROVED]

Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China [version 2; peer review: 2 approved]

A novel coronavirus (2019-nCoV) originating in Wuhan, China presents a potential respiratory viral pandemic to the world population.Current efforts are focused on containment and quarantine of infected individuals.Ultimately, the outbreak could be controlled with a protective vaccine to prevent 2019-nCoV infection.While vaccine research should be p

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Light-phase time-restricted feeding disrupts the muscle clock and insulin sensitivity yet potentially induces muscle fiber remodeling in mice

Skeletal muscle plays a critical role in regulating systemic metabolic homeostasis.It has been demonstrated that time-restricted feeding (TRF) during the rest phase can desynchronize the suprachiasmatic nucleus (SCN) and peripheral clocks, thereby increasing the risk of metabolic diseases.However, the impact of dietary timing on the muscle clock Zi

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